Recombinant FAP anticorps

N° du produit ABIN7543216

Cet anticorps anti-FAP est un anticorps Lapin Chimeric détectant FAP dans IHC, ELISA et FACS. Adapté pour Humain.

Aperçu rapide pour Recombinant FAP anticorps (ABIN7543216)

Antigène: FAP (Fibroblast Activation Protein, alpha (FAP))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp FAP est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Clone: 3F2

Détail du produit anti-FAP anticorps

Fonction: Anti-FAP [3F2], Rabbit IgG, kappa

Specificité: This antibody can bind human, mouse and cynomolgus monkey fibroblast activation protein.

Réactivité croisée: Cynomolgus, Souris

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgG2a

Purification: Protein A affinity purified

Isotype: IgG kappa

Information d'application

Indications d'application: The original mouse antibody was used to check the expression levels of FAP on the surface of GM05389 lung fibroblasts using flow cytometry. The original mouse IgG1 version of this antibody binds human, mouse and cynomolgus monkey FAP with an avidity of 39 pM, 29 pM and 42 pM respectively. Binding of human IgG1 antibody 3F2 to human and murine FAP expressed on stably transfected HEK293 cells, human fibroblasts cell line GM05389 was measured by floy cytometry. The mouse IgG2a version of this antibody was also used for the immunohistochemical stainings of frozen tissue microarray (TMA) containing 10 invasive ductal carcinomas of the breast, 10 colorectal adenocarcinomas and 10 non-small cell lung cancers (US20200079873).

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format for improved compatibility with existing reagents assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur FAP

Antigène: FAP (Fibroblast Activation Protein, alpha (FAP))

Autre désignation: FAP

Sujet: Seprase, Fibroblast activation protein, Prolyl endopeptidase FAP, 170 kDa melanoma membrane-bound gelatinase, Dipeptidyl peptidase FAP, FAPalpha, Fibroblast activation protein alpha, Gelatin degradation protease FAP, Integral membrane serine protease, Post-proline cleaving enzyme, Serine integral membrane protease, SIMP, Surface-expressed protease

UniProt: Q12884

Pathways: Tube Formation